CVN293

CVN293
  • CAS No.:2815296-08-1
  • Grade:99.91%
  • Formula:C14H10FN7O
  • M.W.:311.27

Overview

CVN293 is a selective and brain permeable potassium ion (K + ) channel KCNK13 inhibtor with IC 50 s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1β in microglia.

Application

Products | Products > Disease Areas > Pain | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

  • Catalog No.: HY-158155
  • CAS No.: 2815296-08-1
  • Molecular Formula: C14H10FN7O
  • Molecular Weight: 311.27
  • Purity: 99.91%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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