LBA-3

Overview

LBA-3 is a selective, orally active inhibitor for sodium-coupled citrate transporter SLC13A5 , with an IC 50 of 67 nM. LBA-3 decreases levels of triglyceride and total cholesterol in oleic and palmitic acid (OPA)-stimulated AML12 cells, PCN-stimulated primary mouse hepatocytes and in mouse models, without detectable toxicity. LBA-3 is blood-brain barrier permeable.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-158160
• CAS No.: 2918263-09-7
• Molecular Formula: C18H18O5
• Molecular Weight: 314.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source