AChE-IN-63

Overview

AChE-IN-63 (Compound 5AD) is a selective inhibitor of hAChE ( IC 50 =0.103 μM). AChE-IN-63 also inhibits hBChE and hBACE-1 ( IC 50 = 10 μM (hBChE); 1.342 μM (hBACE-1)). AChE-IN-63 inhibits Aβ aggregation, preventing the formation and deposition of Aβ1-42. AChE-IN-63 can effectively penetrate the blood-brain barrier and is orally effective. It is primarily used in Alzheimer's disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Beta-secretase

Product Information

• Catalog No.: HY-158261
• CAS No.: 876685-78-8
• Molecular Formula: C18H19N5O
• Molecular Weight: 321.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source