PROTAC EGFR degrader 13

Overview

PROTAC EGFR degrader 13 (compound 106) is an EGFR PROTAC degrader with a DC 50 of <0.1 μM. PROTAC EGFR degrader 13 has proliferation inhibitory activity on cell Ba/F3-TEL-EGFR-T790M-L858R-C797S with an IC 50 of 15.6 nM. PROTAC EGFR degrader 13 can be used for the study of EGFR-related diseases such as cancer . (Pink: Target protein ligand; Blue: Cereblon ligand ( HY-14658 ); Black: linker ( HY-W262798 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-158313
• CAS No.: 2861227-35-0
• Molecular Formula: C49H55BrN11O6P
• Molecular Weight: 1004.91
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source