PROTAC ATM degrader-1

Overview

PROTAC ATM degrader-1 is a ATM PROTAC degrader with a K D value of 1.17 nM. PROTAC ATM degrader-1 triggers DNA damage response, cell cycle arrest, and apoptosis in cancer cells via the ubiquitin-proteasome-dependent degradation pathway. PROTAC ATM degrader-1 can be used for research on colorectal cancer . (Pink: ATM ligand ( HY-185575 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-130544 )).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > ATM/ATR | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-158345
• CAS No.: 2821804-13-9
• Molecular Formula: C49H55N9O6S
• Molecular Weight: 898.08
• Purity: 98.01%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source