KSI-6666

Overview

KSI-6666 is an orally active, competitive antagonist for sphingosine 1-phosphate receptor 1 ( S1PR1 ), with an IC 50 of 6.4 nM. KSI-6666 exhibits anti-inflammatory efficacy in autoimmune encephalomyelitis model and T cell transfer colitis model.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor

Product Information

• Catalog No.: HY-158417
• CAS No.: 1807873-14-8
• Molecular Formula: C23H26ClF3N2O2
• Molecular Weight: 454.91
• Purity: 96.15%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source