MAO-B-IN-33

Overview

MAO-B-IN-33 (compound C3) is a potent, reversible and selective monoamine oxidase-B ( MAO-B ) inhibitor with an IC 50 of 0.021 μM and 26.805 μM for MAO-B and MAO-A , respectively. The selectivity of MAO-B-IN-33 is attributed to the steric clash arising from the residue differences between Phe208 ( MAO-A ) and Ile199 ( MAO-B ). MAO-B-IN-33 inhibits cerebral MAO-B activity and alleviates MPTP ( HY-15608 )-induced dopaminergic neuronal loss in the mouse. MAO-B-IN-33 has the potential for Parkinson's disease research .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Monoamine Oxidase

Product Information

• Catalog No.: HY-158732
• CAS No.: 2286257-25-6
• Molecular Formula: C18H19FN2O2
• Molecular Weight: 314.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source