PROTAC IRAK4 degrader-10

Overview

PROTAC IRAK4 degrader-10 (compound 10) is an oral active PROTAC based on Cereblon ligand , and induces the degradation of IRAK4 with maximum degradation of 95.94% and the DC 50 of 7.68 nM in HEK293 cells (Sturcture Note:(Blue: Cereblon ligand , Black: linker；Pink: IRAK4 ligand).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > IRAK

Product Information

• Catalog No.: HY-158758
• CAS No.: 3033829-95-4
• Molecular Formula: C43H45F3N8O6
• Molecular Weight: 826.86
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source