Aprocitentan

Overview

Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC 50 s of 3.4 nM and 987 nM, and pA 2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent.

Application

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Product Information

• Catalog No.: HY-15895
• CAS No.: 1103522-45-7
• Molecular Formula: C16H14Br2N6O4S
• Molecular Weight: 546.19
• Purity: 99.55%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.58 mM); Clear solution
• Availability: In-stock

Source

Original product source