BD-AcAc2

Overview

BD-AcAc2 (R,S-1,3-Butanediol acetoacetate diester) is an orally active, CNS-penetrant antiepileptic agent. BD-AcAc2 inhibits NF-κB , NLRP3 inflammasome, caspase-1/3 , pyroptosis , apoptosis , and enhances autophagy . BD-AcAc2 exhibits antioxidant activity by modulating ROS , MDA, SOD , and GSH levels, and alleviates oxidative stress . BD-AcAc2 mitigates chronic colitis, counteracts Dextran Sodium Sulfate (DSS)-induced pathology, protects against central nervous system oxygen toxicity and acute lung injury, and exhibits anti-seizure efficacy . BD-AcAc2 can be used for the research of colitis, sarcopenia, acute lung injury, seizure, and obesity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Epilepsy | Products > Disease Areas > Acute Lung Injury | Products > Disease Areas > Colitis | Products > Disease Areas > Obesity | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Oxidative Phosphorylation | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Pyroptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-159007
• CAS No.: 58213-75-5
• Molecular Formula: C12H18O6
• Molecular Weight: 258.27
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source