Mal-Val-Ala-PAB-N(SO2Me)-Exatecan

Overview

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan ( HY-13631 ) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 ( DLL3 , K D =58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer .

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Drug-Linker Conjugates for ADC

Product Information

• Catalog No.: HY-159072
• CAS No.: 2575682-08-3
• Molecular Formula: C56H65FN8O15S
• Molecular Weight: 1141.22
• Purity: 98.84%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution
• Availability: In-stock

Source

Original product source