PROTAC SMARCA2 degrader-7

Overview

PROTAC SMARCA2 degrader-7 (Compound I-428) is a PROTAC degrader for SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A (SMARCA) SMARCA2 . PROTAC SMARCA2 degrader-7 degrades SMARCA2 and SMARCA4 in MV411 with DC 50 of <100 and 100-500 nM. (Pink: Ligand for target protein ( HY-159542 ); Black: Linker ( HY-159538 ); Blue: Ligand for E3 ligase (S,R,S)-AHPC ( HY-125845 ))

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-159451
• CAS No.: 2568277-71-2
• Molecular Formula: C50H62N10O5S
• Molecular Weight: 915.16
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source