Sabialimon P (compound 16) is a NO release inhibitor ( IC 50 =18.12 μM) with anti-inflammatory activity. Sabialimon P significantly reduces the secretion of TNF-α , iNOS , IL-6 and NF-κB and inhibits the expression of COX-2 and NF-κB/p65 in RAW264.7 cells induced by LPS ( HY-D1056 ).
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > COX | Products > Signaling Pathways > Interleukin Related
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