PF-07899895

Overview

PF-07899895 (Compound 34) is a SIK inhibitor, with IC 50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1 , SIK2 , and SIK3 , respectively. PF-07899895 modulates the anti-inflammatory cytokine IL-10 in immune cells. PF-07899895 is applicable to research related to inflammatory diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Salt-inducible Kinase (SIK) | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-159657
• CAS No.: 3033846-10-2
• Molecular Formula: C23H23N5OS
• Molecular Weight: 417.53
• Purity: 98.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source