AMD 3465

Overview

AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4 , inhibits binding of 12G5 mAb and CXCL12 AF647 to CXCR4 , with IC 50 s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains ( IC 50 : 1-10 nM), but has no effect on CCR5-using (R5) viruses.

Application

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Product Information

• Catalog No.: HY-15971A
• CAS No.: 185991-24-6
• Molecular Formula: C24H38N6
• Molecular Weight: 410.60
• Purity: 98.24%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source