AMD 3465 (Standard)

Overview

AMD 3465 (Standard) is the analytical standard of AMD 3465. This product is intended for research and analytical applications. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4 , inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4 , with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Others | Products > Research Areas > Infection | Products > Research Areas > Endocrinology | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-15971AR
• CAS No.: 185991-24-6
• Molecular Formula: C24H38N6
• Molecular Weight: 410.60
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source