AMD 3465 hexahydrobromide (Standard)

Overview

AMD 3465 (hexahydrobromide) (Standard) is the analytical standard of AMD 3465 (hexahydrobromide). This product is intended for research and analytical applications. AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4 , inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4 , with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.

Application

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Product Information

• Catalog No.: HY-15971R
• CAS No.: 185991-07-5
• Molecular Formula: C24H44Br6N6
• Molecular Weight: 896.07
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source