Rodatristat ethyl

Overview

Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Tryptophan Hydroxylase | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-101124
• CAS No.: 1673571-51-1
• Molecular Formula: C29H31ClF3N5O3
• Molecular Weight: 590.04
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.53 mM); Clear solution
• Availability: In-stock

Source

Original product source