COX-1-IN-5

Overview

COX-1-IN-5 (example 13, compound PS13) is a potent and selective COX-1 inhibitor ( COX-1 IC 50 = 1 nM, COX-2 IC 50 > 0.1 μM) exhibiting >1000-fold selectivity over COX-2 . COX-1-IN-5 possesses strong anti-inflammatory, antipyretic, analgesic, antithrombotic, anti-cancer activities. COX-1-IN-5 can be used for COX-mediated diseases research, such as inflammatory conditions and pain. COX-1-IN-5 radiolabeled with 11 C can be used as a selective PET tracer for whole‑body imaging of COX‑1 distribution and target engagement in vivo.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-160184
• CAS No.: 524699-85-2
• Molecular Formula: C18H16F3N3O3
• Molecular Weight: 379.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source