MG-1102

Overview

MG-1102 is first-in-class dual binder of monomeric tau and pre-miRNA-146a . MG-1102 shows specific inhibition of miRNA146a with IC 50 s of 0.21 mM and 0.36 mM specific inhibition of doublelabeled pre-miRNA146a and mono-labeled pre-miRNA146a, respectively. MG-1102 interacts with tau monomers with a K d of 3.21 mM by surface plasmon resonance (SPR). MG-1102 is a potential multi-target-directed ligands (MTDLs) for Alzheimer’s disease (AD).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Tau Protein | Products > Signaling Pathways > MicroRNA

Product Information

• Catalog No.: HY-160481
• CAS No.: 2567913-75-9
• Molecular Formula: C22H18N4OS
• Molecular Weight: 386.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source