PF-05214030

Overview

PF-05214030 is a TRPV4 antagonist ( IC 50 : 4 and 27nM for hTRPV4 and rTRPV4 respectively). PF-05214030 reverses the reduction in bladder capacity caused by intravesical infusion of a TRPV4 agonist.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Others | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-160603
• CAS No.: 1669444-50-1
• Molecular Formula: C17H13Cl2FN2O4S
• Molecular Weight: 431.27
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.59 mM); Clear solution
• Availability: In-stock

Source

Original product source