Aleniglipron

Overview

Aleniglipron (GSBR-1290) is an orally active glucagon-like peptide-1 receptor ( GLP-1R ) agonist, with an EC 50 value of less than 0.1 nM in HDB cell lines in cAMP stimulation assays. Aleniglipron selectively activates the Gαs-cAMP signaling pathway of GLP-1R without β-arrestin recruitment. Aleniglipron induces insulin release, promotes glucose clearance, reduces food intake and decreases body weight. Aleniglipron is applicable to research related to type 2 diabetes and obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-160734
• CAS No.: 2685823-26-9
• Molecular Formula: C49H55FN9O6P
• Molecular Weight: 915.99
• Purity: 99.88%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (2.73 mM); Clear solution
• Availability: In-stock

Source

Original product source