ZB-R-55

Overview

ZB-R-55 is an orally active and selective dual-mode RIPK1 inhibitor with RIPK1 IC 50 values of 5.7 nM. ZB-R-55 occupies both the allosteric and ATP binding sites of RIPK1 . ZB-R-55 inhibits necroptosis in cancer cells. ZB-R-55 can be used for the research of systemic inflammatory response syndrome and sepsis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > Necroptosis

Product Information

• Catalog No.: HY-161059
• CAS No.: 2416593-55-8
• Molecular Formula: C25H23N5O3
• Molecular Weight: 441.48
• Purity: 99.39%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution
• Availability: In-stock

Source

Original product source