CSC-6

Overview

CSC-6 is a NLRP3 inhibitor . CSC-6 can significantly inhibit IL-1β secreted by PMATHP-1 cells with an IC 50 value of 2.3 μM. CSC-6 specifically binds NLRP3 and inhibits NLRP3 activation by blocking ASC oligomerization during NLRP3 assembly. CSC-6 effectively reduces the symptoms of NLRP3 overactivation-mediated sepsis and gout in mouse models.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-161072
• CAS No.: 354559-44-7
• Molecular Formula: C18H12F3NO2S2
• Molecular Weight: 395.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source