Lenalidomide 4'-alkyl-C3-azide

Overview

Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide ( HY-A0003 ) that can be used to synthesize PROTACs . Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-161131
• CAS No.: 2399455-71-9
• Molecular Formula: C16H18N6O3
• Molecular Weight: 342.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source