3,4-DAA is an orally active Anthranilic acid derivative with potent immunosuppressive activities. 3, 4-DAA can alleviate the severity of colitis through inhibiting Th1 cells response, promoting Th2 cytokines expression and inducing CD4 + CD25 + T cells expression. 3,4-DAA suppressed expression of inducible nitric oxide synthase ( iNOS ) and nitric oxide (NO) release from EOC20 cells induced by IFN-γ and Lipopolysaccharide.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NO Synthase
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