(Rac)-EBET-1055

Overview

(Rac)-EBET-1055 is the racemate of EBET-1055 ( HY-161346 ). EBET-1055 is a bromodomain and extra-terminal ( BET ) PROTAC degrader. EBET-1055 effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC). EBET-1055 also simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-161346A
• CAS No.: 3031540-65-2
• Molecular Formula: C51H54N8O9
• Molecular Weight: 923.02
• Purity: 97.17%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (2.71 mM); Clear solution
• Availability: In-stock

Source

Original product source