SIK-IN-3

Overview

SIK-IN-3 (Compound 6B) is an inhibitor for salt-inducible kinase ( SIK ), which inhibits SKI1, SIK2 and SIK3 with IC 50 s of 0.1, 0.3 and 0.8 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC 50 of 0.6 nM, stimulates the LPS ( HY-D1056 ) -induced IL-10 release with EC 50 of 3 nM in human macrophages.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > AMPK

Product Information

• Catalog No.: HY-161442
• CAS No.: 3033845-49-4
• Molecular Formula: C24H25N5OS
• Molecular Weight: 431.55
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source