PROTAC EGFR degrader 10

Overview

PROTAC EGFR degrader 10 (Compound B56) is a PROTAC degrader for epidermal growth factor receptor ( EGFR ), with DC 50 <100 nM. PROTAC EGFR degrader 10 binds CRBN-DDB1 with a K i of 37 nM. PROTAC EGFR degrader 10 degrades EGFR , focal adhesion kinase ( FAK ), and RSK1 , inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC 50 <150 nM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > FAK

Product Information

• Catalog No.: HY-161632
• CAS No.: 3034244-56-6
• Molecular Formula: C49H65ClN10O7S
• Molecular Weight: 973.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source