HSP90-IN-31

Overview

HSP90-IN-31 (compound Be01) causes reduction of CD80 and CD86 expression on dendritic cells (DCs). HSP90-IN-31 decreases the production of pro-inflammatory cytokines ( IL-6 , TNF-α , and IL-1β ) in BMDC and peritoneal macrophages stimulated by LPS ( HY-D1056 ). Under the delayed-type hypersensitivity (DTH) mice model, HSP90-IN-31 reduces ear swelling and pro-inflammatory cytokines in the spleen.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-161833
• CAS No.: 2117645-10-8
• Molecular Formula: C22H28N2O4
• Molecular Weight: 384.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source