MeIm

Overview

MeIm (compound 7) is a high-affinity PCSK9 targeting peptide mimetic with cholesterol-lowering activity. MeIm increases cellular uptake of LDL ( EC 50 =6.04 μM) by inhibiting the binding of PCSK9 to LDLR ( IC 50 =11.2 μM). MeIm can be used in the study of cardiovascular diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > LDLR | Products > Signaling Pathways > PCSK9

Product Information

• Catalog No.: HY-161941
• CAS No.: 2043947-71-1
• Molecular Formula: C22H22N8
• Molecular Weight: 398.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source