Thalidomide-NH-C10-Boc

Overview

Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker , which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 ( HY-161960 ) to produce the PROTAC molecule dCE-2 ( HY-161958 ).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-161961
• CAS No.: 2428400-25-1
• Molecular Formula: C28H39N3O6
• Molecular Weight: 513.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source