YPX-C-05

Overview

YPX-C-05 is an orally active HDAC inhibitor and vasodilator. YPX-C-05 inhibits HDAC enzymatic activity, increases histone H 4 acetylation, activates the PI3K/Akt pathway, promotes Akt and eNOS phosphorylation, enhances eNOS activity, and boosts nitric oxide production. YPX-C-05 increases Tetrahydrobiopterin ( HY-107383 ) levels, restores serum nitric oxide levels, reduces endothelin-1 levels, and improves endothelial function. YPX-C-05 reduces vascular remodeling and exerts antihypertensive effects in hypertensive Mus musculus mice. YPX-C-05 can be used for the research of hypertension.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Akt | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-162060
• CAS No.: 2894823-79-9
• Molecular Formula: C21H19N3O4
• Molecular Weight: 377.39
• Purity: 98.05%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source