CMX410

Overview

CMX410 is an orally active and selective Mycobacterium tuberculosis Pks13 acyltransferase domain inhibitor and anti- bacterial agent. CMX410 reacts with the catalytic serine of the Pks13-AT domain to form a stable β-lactam ring, disables the enzyme’s active site, reduces trehalose monomycolate and trehalose dimycolate levels, triggers cell lysis , and reduces intracellular bacterial burden. CMX410 can be used for the research of tuberculosis.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Acyltransferase | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-162094
• CAS No.: 3027135-80-1
• Molecular Formula: C16H13F3N4O6S2
• Molecular Weight: 478.42
• Purity: 99.79%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source