PROTAC METTL3-14 degrader 1

Overview

PROTAC METTL3-14 degrader 1 is a METTL3-METTL14 heterodimer complex PROTAC degrader. PROTAC METTL3-14 degrader 1 binds to the E3 ubiquitin ligase CRBN , forms a ternary complex with METTL3-METTL14 , and promotes the ubiquitination and degradation of METTL3 . PROTAC METTL3-14 degrader 1 is applicable to the research of acute myeloid leukemia and prostate cancer . (Pink: METTL3-14 ligand ( HY-115717 ); Blue: Cereblon ligand ( HY-10984 ); Black: linker ( HY-168686 )).

Application

Products | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Blood Disease | Products > Disease Areas > Acute Myeloid Leukemia | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > METTL3

Product Information

• Catalog No.: HY-162282
• CAS No.: 3039554-79-2
• Molecular Formula: C51H66F2N12O6
• Molecular Weight: 981.14
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source