BAY-9835

Overview

BAY-9835, a chemical probe, is an orally active ADAMTS7 and ADAMTS12 antagonist with IC 50 s of 6 nM and 30 nM, respectively. BAY-9835 exhibits inhibitory potencies vs mouse (m IC 50 = 8 nM) and rat (r IC 50 = 27 nM) ADAMTS7 enzymes . BAY-9835 is very selective against a range of off-targets and metalloproteases. BAY-9835 can be used for the study of atherogenesis.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > ADAMTS

Product Information

• Catalog No.: HY-162284
• CAS No.: 3032487-31-0
• Molecular Formula: C22H16F5N5O3
• Molecular Weight: 493.39
• Purity: 99.46%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (5.07 mM); Clear solution
• Availability: In-stock

Source

Original product source