ICI 185282

Overview

ICI 185282 is a potent, selective, orally active thromboxane A2 (TXA₂) receptor antagonist. ICI 185282 causes dose-dependent inhibition of U-46619 ( HY-108566 )-induced platelet aggregation ex-vivo in guinea-pig. ICI 185,282 inhibits bronchospasm induced by U-46619 , PGD 2 ( HY-101988 ), PGF 2α ( HY-12956 ), arachidonic acid ( HY-109590 ), LTD 4 and PAF ( HY-108635 ) in vivo. ICI 185282 can be used for bronchial asthma research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Prostaglandin Receptor

Product Information

• Catalog No.: HY-101235
• CAS No.: 106393-80-0
• Molecular Formula: C18H21F3O5
• Molecular Weight: 374.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source