BAL-0028

Overview

BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC 50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with K D values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity.

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-162333
• CAS No.: 2842012-69-3
• Molecular Formula: C24H22FN3O2
• Molecular Weight: 403.45
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.20 mM); Clear solution
• Availability: In-stock

Source

Original product source