EBP-IN-1

Overview

EBP-IN-1 is an orally active, blood-brain barrier-permeable inhibitor of emopamil binding protein ( EBP ). EBP-IN-1 has an IC 50 of 8.2 μM against human ERG potassium channels (in CHO background). By inhibiting the sterol isomerase activity of EBP, EBP-IN-1 causes the accumulation of Zymostenol ( HY-113345 ), and exhibits strong target binding in the brain after repeated administration in rodents. EBP-IN-1 also promotes oligodendrocyte formation in human cortical organoids and can be used in research related to multiple sclerosis.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Emopamil Binding Protein

Product Information

• Catalog No.: HY-162351
• CAS No.: 3034437-44-7
• Molecular Formula: C24H33N3O3
• Molecular Weight: 411.54
• Purity: 99.77%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.07 mM); Clear solution
• Availability: In-stock

Source

Original product source