(14S,15R)-14-Deoxyoxacyclododecindione

Overview

(14S,15R)-14-Deoxyoxacyclododecindione (Compound 3) acts as an inhibitor of TGF-β -dependent Smad2/3 and IL-4 -dependent STAT6 , with IC 50 values of 90 nM and 20 nM, respectively. (14S,15R)-14-deoxyoxacyclododecindione is a potent IL-4 inhibitor with an IC 50 value of 20 nM. (14S,15R)-14-Deoxyoxacyclododecindione is applicable to the research of chronic inflammation and fibrotic diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > STAT | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-162404
• CAS No.: 1899061-36-9
• Molecular Formula: C18H21ClO5
• Molecular Weight: 352.81
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source