PAR4 antagonist 4 (Compound 37) is a selective antagonist for protease activated receptor 4 ( PAR4 ). PAR4 antagonist 3 exhibits antiplatelet efficacy with IC 50 of 14.2 nM. PAR4 antagonist 3 improves metabolic stablility in human liver microsomes with T 1/2 of 42.5 min.
Products | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Others | Products > Signaling Pathways > Protease Activated Receptor (PAR)
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