Yaddle1

Overview

Yaddle1 is an agonist of the mechano-activated ion channel ( Piezo1 ) with a half-maximal effective concentration ( MEC 50 ) of 0.40 μM. Yaddle1 can significantly trigger Ca 2+ inflow in T cells and induce T cell activation response. Yaddle1 can be used in the study of vaccine adjuvants.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Piezo Channel

Product Information

• Catalog No.: HY-162501
• CAS No.: 3041134-13-5
• Molecular Formula: C14H8ClF3N4OS
• Molecular Weight: 372.75
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.71 mM); Clear solution
• Availability: In-stock

Source

Original product source