TLR7 agonist 22

Overview

TLR7 agonist 22 (Compound 11a) emerges as a selective TLR7 agonist with an IC 50 value of 25.86 μM. TLR7 agonist 22 inhibits the cellular HBsAg secretion and effectively activates TLR7 , thereby inducing the secretion of TLR7 -regulated cytokines IL-12 , TNF-αand IFN-αin human PBMC cells. TLR7 agonist 22 is a promising for research in the field of developing novel immunomodulatory anti-HBV agents.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

• Catalog No.: HY-162579
• CAS No.: 3036114-68-5
• Molecular Formula: C20H17FN2O2S
• Molecular Weight: 368.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source