5-HT1AR agonist 1

Overview

5-HT1AR agonist 1 (Compound A3) emerges as a relatively balanced multi-target activity profile, including 5-HT1AR agonist with an EC 50 value of 34 nM, SERT reuptake ihibitor ( IC 50 =12 nM), NET reuptake inhibitor ( IC 50 =78 nM) and DAT reuptake inhibitor ( IC 50 =135 nM). 5-HT1AR agonist 1 performs significant antidepressant effects and exhibits excellent bioavailability and low clearance in mice, which is promising for research in the field of antidepressant drugs.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-162585
• CAS No.: 3048071-20-8
• Molecular Formula: C24H26N4O3
• Molecular Weight: 418.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source