MAO-A/B-IN-3

Overview

MAO-A/B-IN-3 (Compound 12) stands out as a key dual MAO-AChE inhibitor, displaying excellent multi-target efficacy against MAO-A , MAO-B , and AChE with IC 50 values of 67 nM, 29 nM, and 1370 nM respectively. MAO-A/B-IN-3 is adept at altering the A site (hydrophobic ring) and C site (semicarbazone chain) within ketone amine-based MTDLs to bolster the inhibitory potential against MAO-A/B while notably diminishing activity against AChE . MAO-A/B-IN-3 is poised for research applications in the field of neurodegenerative diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-162606
• CAS No.: 315210-31-2
• Molecular Formula: C17H16N4O2
• Molecular Weight: 308.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source