FXIIa-IN-5

Overview

FXIIa-IN-5 (Compound 4J) is an orally active, selective inhibitor for factor XIIa ( FXIIa ), with IC 50 of 21 nM. FXIIa-IN-5 inhibits the intrinsic coagulation pathways, and exhibits anti-inflammatory and antithrombotic activity in Carrageenan ( HY-125474 )-induced mice thrombosis models. FXIIa-IN-5 exhibits moderate pharmacokinetic characteristics and slightly toxicity (at 100 mg/kg).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Thrombin

Product Information

• Catalog No.: HY-162646
• CAS No.: 3047411-80-0
• Molecular Formula: C26H29N7O
• Molecular Weight: 455.55
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source