C3N-Dbn-Trp2

Overview

C3N-Dbn-Trp2 is an inhibitor for ATP-binding cassette transporter ABCB1 . C3N-Dbn-Trp2 inhibits the ABCB1-mediated Rhodamine 123 ( HY-D0816 ) efflux in cells HEK293T and HCT-15 with IC 50 of 5.9 µM and 2.2 µM. C3N-Dbn-Trp2 inhibits the Doxorubicin ( HY-15142A ) efflux, enhances the cytotoxicity of Doxorubicin in ABCB1-expressing cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-162714
• CAS No.: 2631659-57-7
• Molecular Formula: C36H32N4O2
• Molecular Weight: 552.66
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source