PROTAC SMARCA2/4 degrader-33

Overview

PROTAC SMARCA2/4-degrader-33 (compound I-277) is a PROTAC degrader targeting SMARCA2 and SMARCA4 ; it degrades SMARCA2/4 proteins in A549 cells with the DC 50 s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment. (Pink: SMARCA2 and SMARCA4 ligand ( HY-159545 ); Blue: Cereblon ligand ( HY-163927 ); Black: linker ( HY-162791 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-162741
• CAS No.: 2568276-36-6
• Molecular Formula: C44H51N11O4
• Molecular Weight: 797.95
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source