PROTAC SMARCA2 degrader-16

Overview

PROTAC SMARCA2 degrader-16 (compound I-278) is a PROTAC degrader targeting SMARCA2 ; it degrades SMARCA2 proteins in A549 cells with an DC 50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment. (Pink: SMARCA2 and SMARCA4 ligand ( HY-163926 ); Blue: Cereblon ligand ( HY-163927 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-162742
• CAS No.: 2568276-37-7
• Molecular Formula: C41H47N11O4
• Molecular Weight: 757.88
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source