Nivocasan

Overview

Nivocasan (GS 9450; LB-84451) is a pan- caspase inhibitor that irreversibly arrests caspase-1 activity and inhibits that of caspase-8 . Nivocasan inhibits IL-1β cleavage and blocks osteoclast differentiation. Nivocasan inhibits the protein expression of NFATc1 and CSTK.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-16275
• CAS No.: 908253-63-4
• Molecular Formula: C21H22FN3O5
• Molecular Weight: 415.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source